Effects of ING-911, a tryptic hydrolysate from bovine Milk alpha S1-Casein on anxiety of Wistar male rats measured in the conditioned defensive burying paradigm and the elevated-plus maze test
ING-911 is a tryptic hydrolysate from bovine milk that contains as a major component, a peptide corresponding to the 91-100 fragment of the α S1-casein. As diazepam (DZ), ING-911 was found to have an anticonvulsant activity in the pentylenetetrazole-induced seizures test. The aim of this study was to assess the effects of ING-911 on anxiety of Wistar male rats in two behavioural situations that were designed to elicit responses to aversive stimuli: the conditioned defensive burying paradigm and the elevated